Sai was awarded her PhD in 2006 from the School of IT and Electrical Engineering at UQ. Her PhD research focused on Advanced Database and Web Information Systems. Later, she worked at UQ and National ICT Australia as a research scientist, and participated in projects such as DART and SAFE. Sai joined the Centre for Educational Innovation and Technology at UQ as a programmer, and began developing learning tools in 2011.

Sai joined ITaLI in 2014 as a Learning Tools Developer. Her work focuses on developing learning tools and data processing.